We use cell biology, molecular biology, biochemistry, and other modern approaches to study basic cellular processes and related mechanisms.
Right now, we are focusing on using three dimensional culture model to study the mechanisms of epithelial wound healing. The immediate goal of our research is to find pathways that could be used to achieve epithelial tissue repair.
Ultimately, we would like to identify endogenous pathways that could be activated to achieve general tissue repair and regeneration.
At the same time, we are also studying actin and actin-binding proteins, their roles in cell migration and intracellular vesicle trafficking, and their involvement in pathogens escaping the host defense.
The similar molecular machines are not only used by the host for defense, but also used by pathogens for invasion. We hope to understand the precise mechanisms and provide new angles for drug discovery.